What’s the cause?
There is no single known cause for atopic dermatitis (eczema), and it's not completely understood. It's thought to be linked to a range of factors including:
- genetics – research shows that almost 50% of cases are likely to be caused by a mutation of a gene called filaggrin. Other genes are also thought to play a role, including those involved in your immune system. Research has shown about 70% of people with atopic dermatitis have family members with the condition
- the environment – contact with soaps, detergents or other chemicals can trigger dermatitis, as can allergens in our environments such as animal dander or even bugs like bacteria
- your immune system – if you have dermatitis, your immune system often has an overactive response to allergy or inflammation.
This combination means your vital skin barrier is more vulnerable and unable to retain moisture or prevent irritants, allergies, and skin bugs from entering your skin. So your skin tends to feel more dry and itchy, is more likely to get inflamed, and is more susceptible to allergens.
What causes an atopic dermatitis flare-up?
Flare-ups of atopic dermatitis (eczema) can happen as often as 2 or 3 times a month. Triggers can include:
- irritants such as soaps and detergents, and shampoo
- clothes made from materials like wool and synthetic fabrics
- allergens such as latex, house dust mites, pet dander, pollen, or – more rarely – certain foods such as cows’ milk or eggs
- the weather – especially cold and dry weather in winter
- being unwell – having a cold, for example
- skin infections with bacteria or viruses
- having dry skin
- stress – try our tips for how to relieve stress.
You may notice patterns when your dermatitis flares up, linked to your lifestyle and diet. It's important to note these down as this will help in working out triggers and avoiding them.
Getting a diagnosis is important – if you treat atopic dermatitis early before it becomes severe, it’s usually easier to manage.